Characterization of Resting-State and Functional Connectivity Changes in Vestibular Migraine
In this study, which is being conducted in partnership with Emory University, participants with vestibular migraine will undergo a functional Magnetic Resonance Imaging scan (fMRI). The fMRI will study brain anatomy during rest, and also changes in brain activity during short video clips that can induce vertigo. Results will be compared to brain scans of normal subjects, and also those with migraine headaches, who don't have vertigo. We hope to better understand brain areas and neural networks that are involved in generating vestibular symptoms in those with vestibular migraine.
Virtual Reality Based Vestibular Rehabilitation
The main treatment for many vestibular disorders in physical therapy. However, some patients with vestibular problems, like vestibular hypofunction, still don't feel completely back to normal after physical therapy. In partnership with physical therapists at UCSF, we are conducting a study to understand if vestibular physical therapy within the virtual environment can help those with vestibular disorders. In virtual reality, the environment can be carefully controlled, which has advantages to traditional therapy, allowing for difficulty escalation as the subject improves performance. However, there are also challenges, as some patients with vestibular conditions cannot tolerate the virtual environment. We hope to better understand whether or not virtual reality is helpful, and if so, in which conditions do we see the most benefit.
Predictors of Vestibular Treatment Success
In this larger study, we are recruiting subjects with different vestibular disorders in a prospective database that will be able to track the effectiveness of different treatment options, and whether or not certain factors can help predict treatment success.