Clinical trials

Prospective, Open Label, Multicenter Study of the Aerin Medical RhinAer® ARC Stylus for Chronic Rhinitis to continue to evaluate the effectiveness of the RhinAer® ARC Stylus for treating the posterior nasal nerve area to improve symptoms in adults diagnosed with chronic rhinitis.

Sudy Number: NCT04614324

The primary objective of this double-blind, randomized, placebo-controlled, multicenter clinical trial is to evaluate the safety of Autologous Muscle Derived Cells for Gastro-Intestinal Repair (AMDC-GIR) during the 24 months following 2 consecutive treatments of tongue dysphagia in male and female patients who have undergone surgery and/or chemo- and/or radiotherapy for squamous cell cancer of the oropharynx.

Click here for more information. Click here for a short video about the study.

Study Number: NCT05421689

Key individuals

Principal Investigator
Clark Rosen, MD

Please go to the Balance & Falls Center Research page, to learn more.

Key Individuals

Principal Investigator: Jeffery Sharon, MD
Study Coordinator: Maxwell Hum ([email protected])

Early identification and intervention for hearing loss in children is critical to prevent future speech, language, educational, and cognitive impairment. Though universal newborn hearing screening has been highly successful at identifying deaf and hard of hearing babies at birth, there is no subsequent mechanism for hearing screening until the start of school. Currently, preschool hearing screening is highly variable, and outcomes are uncertain. We have partnered with the San Francisco Department of Public Health to optimize screening and follow-up strategies in preschoolers. In an accompanying study, we are recruiting children aged 3-10 with hearing loss or normal hearing, to test different ways of screening for hearing loss. Participants will be compensated for their time. This study will help us better identify hearing loss in preschoolers so they can receive appropriate intervention and be ready for school entry.

Eligiibility: children aged 3-10 years of age with permanent hearing loss, or with normal hearing.

Study number: 15-16293

A new diagnosis of hearing loss is challenging for parents. Learning how to manage many different options for intervention, the medical and community service systems, and a new infant or toddler who may have communication difficulties is taxing to a family's quality of life. In this study, we are interviewing medical, service, and educational providers for deaf and hard-of-hearing infants and toddlers, as well as the parents themselves, to learn how their child's hearing affects the quality of life of the child him/herself, as well as the family unit. From this, we aim to design and validate a survey instrument to measure quality of life in this population. This instrument will help us and others measure how different multidisciplinary interventions help a family and child manage hearing loss.

Eligibility: Deaf and hard-of-hearing children aged 6 months-3 years, with English-speaking parents.

Study Number: 15-16760

Please go to the Head and Neck Cancer clinical trials page to learn more.

Hearing loss is a major cause of speech, language, and educational delay. Hearing loss is more prevalent in non-white ethnic groups, and children whose home language is not English have increased risk for language and educational challenges. In this study, we are examining speech, language, educational, and behavioral outcomes in children who are deaf or hard of hearing and whose home language is not English. By identifying the specific challenges that this group has, we hope to develop targeted interventions to improve outcomes.

Eligiibility: children aged 6-17 years of age with mild-to-moderate OR single-sided permanent hearing loss, whose home language is not English.

Study Number: 15-17261

This is a cross-sectional study of up to 100 participants who are undergoing clinically indicated sinus procedures to treat chronic rhinosinusitis. 50 participants with CRSwNP and 50 participants with CRS without polyps and no features of atopy will be enrolled in the study. Participants will donate leftover sino-nasal secretions and tissue from their procedures. In addition, participants will be subject to medical record review and research questionnaires.

In many instances, these participants will have multiple procedures over time to treat recurrent disease and this study will allow for them to donate leftover biospecimens as many as 9 times.

Study Number: NCT04628442