Neil Bhola, PhD

Assistant Professor
1450 Third St, Rm 209
UCSF Box 0128
San Francisco, CA 94158
United States
About Me 

Neil Bhola, PhD, is an Assistant Professor in the Department of Otolaryngology-Head and Neck surgery at the University of California, San Francisco. He received his PhD in Molecular Pharmacology in 2009 from the University of Pittsburgh. Dr. Bhola finished his Postdoctoral fellowship in Hematology - Oncology at Vanderbilt University in Nashville, Tennessee in September of 2015.

Dr. Bhola is currently working on understanding the role of chromatin regulating proteins in mediating resistance to currently approved drugs in HNSCC. He has recently published that inhibition of the chromatin “reader” BRD4 can overcome cetuximab resistance in both cell line and patient-derived xenograft models of HNSCC. Blockade of BRD4 abrogated the expression of a multitude of growth factor receptors that have been shown to mediate drug resistance. Dr. Bhola is also investigating the immunosuppressive role of BRD4 and other chromatin regulators in relevant drug resistant models of HNSCC. The goal of Dr. Bhola’s research is to novel and high-throughput methodology to understand the chromatin landscape utilized by cancer cells to escape drug targeting.

Specialty: Oncology

Expertise: Molecular mechanisms of drug resistance in cancer

Professional Interests: Deciphering molecular mechanisms of drug resistance in cancer. Development of novel and effective therapeutic strategies. Chromatin dynamics and drug response in Cancer.

Education and Training:

BS: Florida Institute of Technology, Melbourne, FL – Molecular Biology
PhD: University of Pittsburgh, Pittsburgh, PA – Molecular Pharmacology
Postdoctoral: Vanderbilt University, Nashville, TN - Hematology-Oncology
Awards and Honors:

1999 Academic and Athletic Scholarships, Florida Institute of Technology
1999 Phi Eta Sigma, Florida Institute of Technology
2006 John S Lazo Cancer Pharmacology Predoctoral Fellowship
2011 San Antonio Breast Cancer Symposium Clinical Scholars Fellowship
2012 Susan G Komen for the Cure Postdoctoral Fellowship
2012 Second place Prize VICC Retreat Poster Competition
2014 First place Prize VICC Retreat Poster Competition
2015 AACR Minority Scholar in Cancer Research Award
2016 Brandon Gromada Head and Neck Cancer Foundation Research Award